Charcot-Marie-Tooth Disease (CMT)
-Charcot-Marie-Tooth disease (CMT) is a
neuromuscular disorder characterized by length-dependent degeneration of the
motor and sensory nerve fibers, with a prevalence of 1 in 2,500 (about 200,000
patients in the European Union).
-Anesthesia is administered to this population
more frequently than to normal people, as CMT patients often need orthopedic
surgery to correct muscle imbalance and limb deformities, and for osteosynthesis
of bone fractures as they are prone to falls.
Anesthetic Management Complications:
1-Malignant hyperthermia.
2-Prolonged responses to neuromuscular blocking
drugs.
3-Drug toxicity is caused by inappropriate doses in
case of severe muscle wasting.
4-Medication-induced exacerbation of neuropathy.
5-Associated deformities such as scoliosis.
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